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Advances in pharmacology have permitted more specific targeting of receptors, and greater selectivity of agents, which necessitates greater precision when describing these agents and their effects: Doctors often administer sedatives to patients in order to dull the patient's anxiety related to painful or anxiety-provoking procedures.Although sedatives do not relieve pain in themselves, they can be a useful adjunct to analgesics in preparing patients for surgery, and are commonly given to patients before they are anaesthetized, or before other highly uncomfortable and invasive procedures like cardiac catheterization, colonoscopy or MRI.

This is an important feature considering that prescription drug abuse/overdose now accounts for one of the leading causes of preventable death in our country.

Through many years, the standard care has been to use continuous sedation of critically ill patients during mechanical ventilation.

However, preliminary randomised clinical trials indicate that it is beneficial to reduce the sedation level.

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